Who Funds Defi Startups in Massachusetts?

Real, verified funding sources for defi founders in Massachusetts: VC funds, accelerators, angel networks, and active grant programs — sourced from SEC filings and Grants.gov, not estimates.

No funds headquartered in Massachusetts matched "Defi" by name — the funds below are shown nationwide instead.

Defi Funding Snapshot — Massachusetts (as of July 2026)

  • 1
    5 VC funds (nationwide)with "Defi" in their name — none headquartered in Massachusetts in our data
  • 2
    7 acceleratorsopen to defi founders in Massachusetts (including globally-available programs)
  • 3
    6 angel networksbased in Massachusetts
  • 4
    52 open grantsin the Technology category, refreshed nightly from Grants.gov

Defi VC Funds (Nationwide)

Define Ventures Fund II, L.P.

📍 San Francisco, CA📅 Filed October 2020

General partners: Lynne Chou O'Keefe

$200M
Effective fund size

Define Ventures Fund I, L.P.

📍 San Francisco, CA📅 Filed October 2018

General partners: Lynne Chou O'Keefe

$87.6M
Effective fund size

Definition I LP

📍 New York, NY

General partners: Theodore Citrin, Weston Reynolds

$75M
Effective fund size

FINTECH COLLECTIVE DEFI FUND I LP

📍 Grand Cayman, E9📅 Filed June 2021

General partners: BROOKS GIBBINS, GARETH JONES

$50M
Effective fund size

Definition II LP

📍 New York, NY

General partners: Theodore Citrin, Weston Reynolds

Fund size not reported

Defi Accelerators Open to Massachusetts

7 programs

Techstars Boston

Boston, MA

Techstars Boston

$120K
Deadline: Rolling / no fixed deadline
Learn More →

Visible Hands

Boston, MA

Visible Hands

$100K
Deadline: Rolling / no fixed deadline
Learn More →

Rough Draft Ventures

Cambridge, MA

Rough Draft Ventures

$25K
Deadline: Rolling / no fixed deadline
Learn More →

MIT delta v

Cambridge, MA

MIT delta v

$20K
Deadline: Rolling / no fixed deadline
Learn More →

MassChallenge

Boston, MA

MassChallenge

Varies
Deadline: Rolling / no fixed deadline
Learn More →

Harvard Innovation Labs

Boston, MA

Harvard Innovation Labs

Varies
Deadline: Rolling / no fixed deadline
Learn More →

Alliance DAO

Global

Alliance DAO

$250K - $500K
Deadline: Rolling / no fixed deadline
Learn More →

Angel Investor Networks in Massachusetts

6 networks

Seraf

👥 500 members💰 $5K - $200K check range

📍 Cambridge, MA

TechnologyHealthcareConsumerFintechSaaS

Harvard Business School Angels

👥 150 members💰 $25K - $250K check range

📍 Boston, MA

TechnologyHealthcareConsumerFintechSaaS

Keiretsu Forum Northeast

👥 90 members💰 $25K - $500K check range

📍 Boston, MA

TechnologyHealthcareConsumerFintechSaaS

Launchpad Venture Group

👥 110 members💰 $25K - $250K check range

📍 Boston, MA

TechnologyHealthcareSoftware

TBD Angels

👥 103 members💰 $8K - $125K check range

📍 MA

TechnologyGeneral

MIT Angels

👥 100 members💰 $25K - $200K check range

📍 Cambridge, MA

TechnologyDeep TechLife SciencesHardware

Grants in the Technology Category

Defi falls under the broader "Technology" category in federal grant data. These are federal programs open to eligible founders nationwide (including Massachusetts) — live from Grants.gov, refreshed nightly.

?Defi Funding FAQs — Massachusetts

Are there defi VCs headquartered in Massachusetts?

We don't have any funds headquartered in Massachusetts whose name references defi. Below are defi-related funds from across the country instead — many invest outside their home state.

What accelerators in Massachusetts support defi startups?

7 accelerator programs open to Massachusetts-based defi founders are in our database, including programs based in Massachusetts and globally-available programs.

Are there angel investor networks in Massachusetts?

Yes — 6 angel investor networks based in Massachusetts are in our database, ranked by member count with defi-relevant groups surfaced first where our sector data supports it.

What grants are available for defi founders?

52 currently open federal grant programs are tagged under the Technology category, which is where defi falls in our grant classification. These are federal programs open to eligible founders nationwide (including Massachusetts), pulled live from Grants.gov and refreshed nightly.

Your Defi Funding Action Plan

1

Research & Prepare

  • Review the 5 defi-matched funds above and their filing history
  • Check each fund's website for current investment criteria before reaching out
  • Prepare a pitch deck and financial projections tailored to your stage
2

Apply & Connect

  • Apply to the 7 accelerator programs listed above
  • Reach out to the 6 angel networks in Massachusetts
  • Check eligibility for the 6 open grant programs above
3

Follow Up

  • Track deadlines for any application-based programs above
  • Look for warm introductions through your existing network before cold outreach
  • Revisit this page periodically — fund and grant data refreshes nightly