Who Funds Startups Startups in South Carolina?

12 venture funds, 6 angel networks, 6 accelerator programs and 6 active federal grants for startups founders in South Carolina — sourced from SEC Form D filings and Grants.gov.

17
VC Funds Based in South Carolina
$435M
Capital in SEC Form D Filings
3
New Fund Filings (12 mo)

Venture Capital Funds Investing in StartupsSouth Carolina

Location
SPARTANBURG, SC
Fund Size (Form D)
Undisclosed
Latest SEC Filing
Jul 22, 2025
Location
GREENVILLE, SC
Fund Size (Form D)
$10M
Stage Focus
seed
Typical Check
$250K - $750K (typical: $500K)
Latest SEC Filing
Jan 2, 2024
Location
Mt. Pleasant, SC
Fund Size (Form D)
$250M
Stage Focus
growth
Latest SEC Filing
May 1, 2023
Location
GREENVILLE, SC
Fund Size (Form D)
$10M
Stage Focus
seed
Latest SEC Filing
Jan 21, 2022
Location
CHARLESTON, SC
Fund Size (Form D)
Undisclosed
Latest SEC Filing
May 27, 2021
Location
FORT MILL, SC
Fund Size (Form D)
Undisclosed
Latest SEC Filing
Aug 31, 2020
Location
COLUMBIA, SC
Fund Size (Form D)
$10M
Stage Focus
seed
Typical Check
$117K - $351K (typical: $234K)
Location
CHARLESTON, SC
Fund Size (Form D)
$100M
Stage Focus
growth
Location
AIKEN, SC
Fund Size (Form D)
Undisclosed
Stage Focus
multi-stage
Location
GREENVILLE, SC
Fund Size (Form D)
Undisclosed
Typical Check
$500K - $1.5M (typical: $1.0M)
Location
Charleston, SC
Fund Size (Form D)
Undisclosed
Latest SEC Filing
May 18, 2026
Location
CLEMSON, SC
Fund Size (Form D)
$10M
Stage Focus
seed
Latest SEC Filing
May 8, 2026

Angel Networks in South Carolina

Charleston Angel Partners

Location
SC
Members
53
Avg Check
$25K
Website →

Charleston Angel Partners

Location
Charleston, SC
Members
50
Avg Check
$25K
Website →

VentureSouth

Location
SC
Members
44
Avg Check
$25K
Website →

Spartanburg Angels

Location
Spartanburg, SC
Members
30
Avg Check
$25K
Website →

Greenville Angels

Location
Greenville, SC
Members
30
Avg Check
$25K
Website →

South Carolina Research Authority (SCRA)

Location
SC
Members
28
Avg Check
$25K
Website →

Accelerators & Startup Programs for Startups Founders

Black Ambition

Black Ambition

Funding: $1M

Apply →

Elemental Impact

Elemental Impact

Funding: $1M

Apply →

Lemnos

Lemnos

Funding: $500K

Apply →

Y Combinator

Y Combinator

Funding: $500K

Apply →

Alliance DAO

Alliance DAO

Funding: $250K – $500K

Apply →

Contrary Capital

Contrary Capital

Funding: $500K

Apply →

See the full accelerator directory for industry-specific programs.

Active Federal Grant Opportunities

Statewide Consumer Network

Substance Abuse and Mental Health Services Adminis

Award
Undisclosed – $150K
Deadline
Jun 24, 2026
View on Grants.gov →

U.S. STEM Summer Exchange for Youth

U.S. Mission to the Dominican Republic

Award
$30K – $80K
Deadline
Jun 24, 2026
View on Grants.gov →

FY 2026 Pipeline One-Call Grant

Pipeline and Hazardous Materials Safety Admin

Award
$100.00 – $60K
Deadline
Jun 24, 2026
View on Grants.gov →

BRAIN Initiative: Data Archives for the BRAIN Initiative (R24 Clinical Trial Optional)

National Institutes of Health

Deadline
Jun 24, 2026
View on Grants.gov →

FY 2026 State Damage Prevention

Pipeline and Hazardous Materials Safety Admin

Award
$4K – $100K
Deadline
Jun 24, 2026
View on Grants.gov →

Center of Excellence on Eating Disorders

Substance Abuse and Mental Health Services Adminis

Award
Undisclosed – $2M
Deadline
Jun 24, 2026
View on Grants.gov →

Browse all federal startup grants with deadlines and eligibility.

Data sources: Fund data comes from SEC Form D filings (EDGAR), updated nightly. Grant opportunities come from Grants.gov. Angel network and accelerator data is curated from public sources. Figures shown are the amounts reported in regulatory filings, not estimates. Last refreshed June 2026.