Complete funding guide for life sciences entrepreneurs in Connecticut. Find 8 VC funds, 5 accelerators,4 angel networks, and 4 grant opportunities.
The life sciences startup ecosystem in Connecticut has experienced remarkable growth, with $481M in funding across 201 deals in 2025.This represents 11% year-over-year growth compared to the previous year, positioning Connecticutas a emerging market forlife sciences innovation.
The average funding round size of $3M reflects strong investor confidence in Connecticut-based life sciences startups. Competition levels are currently moderate, with 8 active VC funds specifically targeting this sector.
Connecticut offers a concentrated life sciences ecosystem with specialized talent
Strong government support for life sciences innovation and R&D tax incentives
Access to leading universities and research institutions in the region
Lower operational costs compared to traditional tech hubs like San Francisco
series-b stage focus • 37 portfolio companies
series-b stage focus • 20 portfolio companies
seed stage focus • 20 portfolio companies
series-b stage focus • 38 portfolio companies
series-b stage focus • 38 portfolio companies
seed stage focus • 51 portfolio companies
series-b stage focus • 59 portfolio companies
seed stage focus • 59 portfolio companies
📍 Connecticut
📍 Connecticut
📍 Connecticut
📍 Connecticut
by Connecticut Innovation Agency
Life Sciences startups based in Connecticut
by Connecticut Innovation Agency
Life Sciences startups based in Connecticut
by Connecticut Innovation Agency
Life Sciences startups based in Connecticut
by Connecticut Innovation Agency
Life Sciences startups based in Connecticut
Strong funding activity as VCs deploy fresh capital from annual fund raises
Peak investment period with increased deal velocity and accelerator demo days
Moderate activity as partners focus on portfolio company support during summer
Year-end push to deploy remaining capital and close pending deals
Life Sciences startup funding in Connecticut is moderate, with 8 active VC funds and 5 accelerator programs competing for deals. The acceptance rate for top-tier funding is approximately 2-5%, making it essential to have strong traction metrics, a compelling business model, and clear differentiation from competitors. Success factors includeDeep expertise in life sciences domain, Strong technical team with proven track record, Clear market validation and customer traction.
Life Sciences startups in Connecticut raise an average of $3M per funding round, based on 201 deals completed in 2025. This represents 11% year-over-year growthcompared to the previous year. Seed rounds typically range from $500K to $3M, while Series A rounds average $3M to $15M depending on market traction and business model scalability.
Top life sciences accelerators in Connecticut report success rates of 75-85% for follow-on funding, with program lengths ranging from 12-16 weeks and equity terms of 4-7%. The most successful programs focus onlife-sciences and startup-growthand provide extensive mentor networks, investor connections, and post-graduation support lasting 2+ years.
Connecticut offers several unique advantages for life sciences startups: Connecticut offers a concentrated life sciences ecosystem with specialized talent, Strong government support for life sciences innovation and R&D tax incentives, and Access to leading universities and research institutions in the region. The local ecosystem includes 8 specialized VC funds, 4 angel networks, and 4 grant programs specifically supporting life sciences innovation.
The optimal fundraising months in Connecticut are February, March, May, when investor activity peaks and deal velocity increases. Q1 typically sees strong funding activity as vcs deploy fresh capital from annual fund raises, while Q4 shows year-end push to deploy remaining capital and close pending deals. Allow 4-6 months for the complete fundraising process, including preparation, pitching, due diligence, and closing.
The most effective approach combines warm introductions, industry events, and direct outreach. Start by leveraging your network for introductions to the 8 active VC funds in Connecticut. Join relevant life sciences meetups, attend pitch competitions, and participate in accelerator demo days. Angel networks like Connecticut Life Sciences Angels host regular investor meetings and can provide valuable early-stage funding and mentorship.
Last updated: 12/10/2025 | Data aggregated from 8 VC funds, 5 accelerators, and 4 angel networks |About our methodology