Life Sciences Startup Funding in Massachusetts

Connect with 5+ venture capital funds investing in Life Sciences startups across Massachusetts.

5
Active VC Funds
$3.3M
Median Check Size
3
Recent Filings (90d)
$0.0B
Total AUM

Massachusetts Venture Capital Landscape

Ecosystem Overview

Massachusetts ranks #4 globally for startup ecosystem strength, with over 5,200 active startups and15 unicorn companies.

The state has seen 52 successful exits in the past 12 months, demonstrating strong investor confidence and market maturity.

Top Investment Sectors

Life SciencesArtificial IntelligenceFintech

Market Insights

Investment Climate

Research-driven ecosystem with world-class universities and deep biotech expertise

Funding Trends

Strong biotech and AI focus with university research partnerships

Emerging Opportunities

Precision MedicineAI Drug DiscoveryDigital Therapeutics

Life Sciences VC Funds Directory

General Catalyst

Massachusetts

$3M
Min. Investment

Investment Focus

Life SciencesArtificial Intelligence
Last Filing: 2024-11-15Learn More →

Matrix Partners

Massachusetts

$2M
Min. Investment

Investment Focus

Life SciencesEnterprise Software
Last Filing: 2024-11-18Learn More →

Polaris Partners

Massachusetts

$4M
Min. Investment

Investment Focus

Life SciencesBiotech
Last Filing: 2024-11-12Learn More →

Atlas Venture

Massachusetts

$2.5M
Min. Investment

Investment Focus

Life SciencesArtificial Intelligence
Last Filing: 2024-11-16Learn More →

Flagship Pioneering

Massachusetts

$5M
Min. Investment

Investment Focus

Life SciencesBiotech
Last Filing: 2024-11-14Learn More →

How to Approach Massachusetts VCs

1. Research & Targeting

  • • Review recent portfolio companies and investment thesis
  • • Analyze check sizes and stage preferences
  • • Look for sector-specific expertise and connections
  • • Check partner backgrounds and interests

2. Warm Introductions

  • • Leverage portfolio company founders for introductions
  • • Connect through accelerator programs and events
  • • Use LinkedIn and mutual connections effectively
  • • Attend Massachusetts startup and investor meetups

3. Pitch Preparation

  • • Tailor your pitch to the fund's investment criteria
  • • Highlight local market opportunities and advantages
  • • Prepare detailed financial projections and metrics
  • • Show clear path to next funding milestones

Frequently Asked Questions

What's the average check size for Massachusetts VC funds?

Massachusetts VC funds typically invest between $3.3M per round, with early-stage funds focusing on $500K-$2M seed rounds and growth funds writing checks of $10M+. The median check size is $3.3M.

How long does the fundraising process typically take?

Most Massachusetts startups take 3-6 months to close their funding round, from initial outreach to signed term sheet. This includes 2-4 weeks for initial meetings, 4-8 weeks for due diligence, and 2-4 weeks for legal documentation.

What do Life Sciences investors look for in startups?

Life Sciences investors in Massachusetts typically focus on strong technical teams, defensible technology, large addressable markets, and clear go-to-market strategies. They also value domain expertise and previous life sciences experience.

Top Life Sciences VC Funds in Massachusetts | Free Startup Funding